Natural Product Biosynthesis, Engineering, and Drug Discovery

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Schedule of events


8:15 a.m. Pick up name badge
8:30 a.m. Welcome and Introduction
Ben Shen, Professor, School of Pharmacy, UW-Madison
       (1991-1995)
8:35-8:40 a.m. Welcome
Jeanette Roberts, Dean and Professor, School of Pharmacy,
        UW-Madison
8:40-9:10 a.m. “Linear Replicons and Secondary Metabolism in Streptomyces
Haruyasu Kinashi, Professor, Hiroshima University,
        Hiroshima, Japan (1984-1986)
9:10-9:40 a.m. “Antibiotics, Pathways and Actinomycetes: Exporting the Hutchinson Culture”
Stefano Donadio, Ph.D., KtedoGen, Milano, Italy
        (1985-1988)
9:40-10:10 a.m. “Current Studies on Geldanamycin Production in Streptomyces hygroscopicus 17997”
Yiguang Wang, Professor, Institute of Medicinal Biotechnology,
        Beijing, China (1989-1990, 1991-1993)
10:10-10:30 a.m. Break
10:30-11:00 a.m. “Effects and New Functions of S-Adenosylmethionine in Streptomyces spp”
Joo-Won Suh, Professor, Myongji University, Gyunggido,
        Korea (1989-1990)
11:00-11:30 a.m. “Novel Epothilones: Chemistry and Biology”
Li Tang, Professor, Dalian University of Technology, Dalian,
        China (1990-1998)
11:30-12:00 p.m. “New and Improved Anti-fungal Polyene Macrolides through Biosynthetic and Chemical Engineering”
Sergey Zotchev, Professor, Norwegian University of Science
        and Technology, Trondheim, Norway (1993-1995)
   
12:00-1:10 p.m. Lunch
   
1:10-1:40 p.m. “Polyketide Lead Optimization: Introducing Structural Diversity by Biosynthetic Engineering”
Steve Kendrew, Ph.D., Biotica Technology, Cambridge, UK
        (1995-1997)
1:40-2:10 p.m. “Continuing the Hutchinson Tradition: Innovative Approaches to Accessing Natural Products”
Kerry Kulowski, Ph.D., Wyeth Research, Pearl River, NY
        (1996-1998)
2:10-2:40 p.m. “Total Engineered Biosynthesis of Antitumor Agent Echinomycin in E. coli
Kenji Watanabe, Professor, University of Southern California,
        Los Angeles, CA (2000-2001)
2:40-3:00 p.m.     Break
3:00-3:30 p.m. “Studies on a New Biosynthetic Pathway for a Vitamin Found in Some Bacteria”
Tohru Dairi, Professor, Toyama Prefectural University, Toyama,
        Japan (1998)
3:30-4:00 p.m. “Manipulation of Natural Product Biosynthetic Machinery for Structural Diversity and Drug Discovery and Development”
Ben Shen, Professor, School of Pharmacy, UW-Madison
        (1991-1995)
4:30 p.m. Reunion picture (in front of Rennebohm Hall)