Our lab is focused on developing biomaterials for combination drug therapy to treat resistant cancers. The goal is to create synthetic materials capable of delivering multiple types of drugs within a single payload, and therefore favorably reduce the dose liming toxicity of individual drugs. We are also interested in using the incredible homing ability of stem cells towards cancer sites as a natural means of delivering drug-loaded nanoparticles (alone or in combination) and testing these new systems in tumor-bearing animals. Ultimately, we believe that effective delivery of chemotherapeutics could reduce the extent of surgery or radiation required in cancer patients.
Drug delivery; biomaterials; stem cells; cancer